The Orbone® Cell and Tissue Bank is a class B GMP licensed facility that processes a wide range of human-derived tissues with a focus on collecting, storing, and processing bone, soft tissues and tissue components. Using licensed and proprietary eCOO® supercritical carbon dioxide technology, it provides superior quality, safe, clean, and innovative products to the Allograft industry.
Traditional cleaning and sterilization methods are generally used in hard bone treatments that affect the mechanical or structural properties of tissue grafts. Several studies show that these methods have detrimental effects on protein structure, adsorption rate, cell adhesion and tensile strength. These procedures also demand meticulous rinsing procedures and very time-consuming procedures.
Conversely, cleaning of tissues with the Orbone® Cell and Tissue Bank’s eCOO® Clean Technology and subsequent eCOO® Ster sterilization minimally affects the structural integrity of the tissue. So far, the sterile level and virus inactivation have reached SAL6. Biomolecular properties (e.g., protein degradation and cell attachment) and mechanical properties (i.e., tensile strength and extreme torque) are retained to support the weight-bearing and/or sensitive application stress of tissue grafts required for tissue-related processing/sterilization using eCOO® scCO2 Technology.

We support the following opportunities in delivering them to you:
- B2B model for R&D and production
- Allograft information support programs for our physicians
- End-to-end service solutions
- Custom production and scaling options
- International distribution and sales opportunities
In addition, the system has been adapted to meet the specific requirements of the tissue and to leave a minimal carbon footprint. The technology has also been modified to minimize its carbon impact and to satisfy the unique needs of the tissue.
Experience with decellularization processes, virus inactivation techniques employing eCOO® technology, and an extra USP add to the product in the case of product development.
The Orbone® Cell and Tissue Bank is a GMP licensed facility that processes a wide range of human-derived tissues with a focus on collecting, storing, and processing bone, soft tissues and tissue components. Using licensed and proprietary eCOO® scCO2 technology, it provides superior quality, safe, clean and innovative products to the Allograft industry.